Lipase active site covalent anchoring of Rh(NHC) catalysts: towards chemoselective artificial metalloenzymes.
نویسندگان
چکیده
A Rh(NHC) phosphonate complex reacts with the lipases cutinase and Candida antarctica lipase B resulting in the first (soluble) artificial metalloenzymes formed by covalent active site-directed hybridization. When compared to unsupported complexes, these new robust hybrids show enhanced chemoselectivity in the (competitive) hydrogenation of olefins over ketones.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 31 شماره
صفحات -
تاریخ انتشار 2015